2 Results for "

Lapaquistat acetate

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Lapaquistat acetate" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-14925
CAS No.: 189059-71-0
Purity:  99.81%
Synonyms: T-91485
Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of Lapaquistat acetate (HY-16274). Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy .
1
1 Cited Publications
Cat. No.: HY-16274
CAS No.: 189060-13-7
Synonyms: TAK-475
Target:  

Farnesyl Transferase

Research Areas:  

Metabolic Disease

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway . Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research .